Rare coding mutations identify 36 large-effect risk genes in obsessive-compulsive disorder and chronic tic disorders. Preprint. B Wang, M Tran, S Wang, ..., J Tischfield, AM Lee, G Heiman, T Fernandez, AJ Willsey, MW State
Sleep-aware adaptive deep brain stimulation to mitigate insomnia in OCD. Brain Stimulation. Noah Guillermo, Leela Mohan, Audrey Kist, Kelly Kadlec, Emma Anderson, Sneha Ray, Joline M. Fan, Philip A. Starr, A Moses Lee
Toward Individualized Deep Brain Stimulation: A Stereoelectroencephalography-Based Workflow for Neurostimulation Target Identification. International Neuromodulation Society. Jeremy Saal, Kelly Kadlec, Anusha B. Allawala, Lucille Johnston, Ryan B. Leriche, Ritwik Vatsyayan, Yiyuan Han, Audrey Kist, Tommaso Di Ianni, Heather E. Dawes, Edward F. Chang, A. Moses Lee, Andrew D. Krystal, Khaled Moussawi, Prasad Shirvalkar, Kristin K. Sellers
- Invasive Brain Mapping Identifies Personalized Therapeutic Neuromodulation Targets for Obsessive-Compulsive Disorder. Translational Psychiatry. A Moses Lee, Audrey Kist, John Alvarez, Kristin K Sellers, Ankit N Khambhati, Leo P Sugrue, Lee B Reid, Kelly Kadlec, Joline M Fan, Anusha B Allawala, Caroline A Racine, Tenzin Norbu, Dani Astudillo, Alexandra G Tremblay-McGaw, Natalie Becker, Ahmad Alhourani, Philip A Starr, Edward F Chang, Andrew D Krystal
Therapeutic DBS for OCD Suppresses the Default Mode Network. Hum Brain Mapp. 2024 Dec 15; 45(18):e70106. Slepneva N, Basich-Pease G, Reid L, Frank AC, Norbu T, Krystal AD, Sugrue LP, Motzkin JC, Larson PS, Starr PA, Morrison MA, Lee AM. PMID: 39719929. View in: PubMed
Intracranial beta activity is a biomarker of circadian and stimulation-induced arousal in obsessive compulsive disorder. Brain Stimul. 2024 Jan-Feb; 17(1):29-31. Fan JM, De B, Frank AC, Basich-Pease G, Norbu T, Morrison MA, Larson P, Starr PA, Krystal AD, Lee AM. PMID: 38097012; PMCID: PMC11539915. View in: PubMed
Tractography-based DBS lead repositioning improves outcome in refractory OCD and depression. Front Hum Neurosci. 2023; 17:1339340. Basich-Pease G, Slepneva N, Frank AC, Norbu T, Morrison MA, Sugrue LP, Larson PS, Starr PA, Lee AM. PMID: 38384668; PMCID: PMC10879278. View in: PubMed
Identification of a personalized intracranial biomarker of depression and response to DBS therapy. Brain Stimul. 2021 Jul-Aug; 14(4):1002-1004. Frank AC, Scangos KW, Larson PS, Norbu T, Lee AT, Lee AM. PMID: 34175247; PMCID: PMC8880609. View in: PubMed
Thalamic transcranial ultrasound stimulation in treatment resistant depression. Brain Stimul. 2024 Sep-Oct; 17(5):1001-1004. Fan JM, Woodworth K, Murphy KR, Hinkley L, Cohen JL, Yoshimura J, Choi I, Tremblay-McGaw AG, Mergenthaler J, Good CH, Pellionisz PA, Lee AM, Di Ianni T, Sugrue LP, Krystal AD. PMID: 39173737; PMCID: PMC11531731. View in: PubMed
Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans. Brain Stimul. 2023 Jul-Aug; 16(4):1072-1082. Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD. PMID: 37385540; PMCID: PMC10634663. View in: PubMed
Closed-loop neurostimulation for the treatment of psychiatric disorders. Neuropsychopharmacology. 2024 Jan; 49(1):163-178. Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD. PMID: 37369777; PMCID: PMC10700557. View in: PubMed
Human Responses to Visually Evoked Threat. Curr Biol. 2021 02 08; 31(3):601-612.e3. Yilmaz Balban M, Cafaro E, Saue-Fletcher L, Washington MJ, Bijanzadeh M, Lee AM, Chang EF, Huberman AD. PMID: 33242389; PMCID: PMC8407368. View in: PubMed
Cell-Type-Specific Control of Brainstem Locomotor Circuits by Basal Ganglia. Cell. 2016 Jan 28; 164(3):526-37. Roseberry TK*, Lee AM*, Lalive AL, Wilbrecht L, Bonci A, Kreitzer AC. PMID: 26824660; PMCID: PMC4733247. View in: PubMed
Between the primate and 'reptilian' brain: Rodent models demonstrate the role of corticostriatal circuits in decision making. Neuroscience. 2015 Jun 18; 296:66-74. Lee AM, Tai LH, Zador A, Wilbrecht L. PMID: 25575943; PMCID: PMC4684574. View in: PubMed
Identification of a brainstem circuit regulating visual cortical state in parallel with locomotion. Neuron. 2014 Jul 16; 83(2):455-466. Lee AM, Hoy JL, Bonci A, Wilbrecht L, Stryker MP, Niell CM. PMID: 25033185; PMCID: PMC4151326. View in: PubMed
Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value. Nat Neurosci. 2012 Sep; 15(9):1281-9. Tai LH*, Lee AM*, Benavidez N, Bonci A, Wilbrecht L. PMID: 22902719; PMCID: PMC3951287. View in: PubMed
